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The KEMRI Wellcome Trust Research Programme (KWTRP) is based within the KEMRI Centre for Geographic Medical Research - (Coast). Our core activities are funded by the Wellcome Trust. We conduct integrated epidemiological, social, laboratory and clinical research in parallel, with results feeding into local and international health policy. Our research platfor...
JOB PURPOSE:
The overall purpose of this post is to undertake research and clinical trials under the human infection (challenge) platform. This will need to be undertaken under good clinical practice ensuring compliance with regulatory, statutory and programme policies in the performance and conduct of clinical trials, patient management including other related clinical and/or research activities and execution of research studies.
The post holder will be responsible for day-to-day oversight of the clinical trials and clinical research activities, develop research ideas. The post holder will work as clinical lead on the project(s) to ensure safety and clinical care of all study volunteers; contribute to tasks preparatory to the project(s), where applicable, to tasks including developing and submitting protocols, developing study work plans, organising, and conducting training for project-specific staff; and ensure compliance of all study staff to good clinical practices and procedures. The post-holder will aid day-to-day organisation and coordination of the research studies and trials, leading safety monitoring on clinical trials, lead and contribute to protocol and SOP development, and day-to-day supervision of clinical staff. Although these are the primary responsibilities, the post-holder will also be involved in higher level responsibilities for ensuring all clinical activities and procedures are carried out to quality standards, managing, and leading the clinical team whilst expected to share the load and as guided by the PI.
This post is open to qualified doctors with a PhD in a relevant field with research experience and will be funded for a three-year period. The post-holder is expected to develop clinical research methods and to execute programme management as well as roles in data management, sample/specimen management, data analysis, and report writing and scientific dissemination through publication writing and presentations. The post is demanding, involving attention to detail and timescales, and strong engagement with various stakeholders and collaborators.
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The KEMRI-Wellcome Trust Research Programme (KWTRP) conducts high quality research on diseases with the highest burden in developing countries. The programme is recognised internationally within the fields of international public health, clinical tropical medicine, epidemiology, and immunology. The programme aims to maximise opportunities for learning and training to maintain a cadre of highly skilled and experienced staff from all disciplines.
The human infection (challenge) platform currently comprises of conducting clinical trials in two disease areas, malaria and Shigella with the aim of aim of accelerating vaccine development through evaluation of investigational products such as vaccines, identifying correlates of protection and/or correlates of immunity, and understanding of naturally acquired immunity. This involves the deliberate infection of healthy volunteers with infection causing agents (e.g., malaria and Shigella).
The post holder will need to be self-sufficient and be able to work with minimal supervision against demanding yet often unpredictable timelines. The post is mentally demanding and involves a high level of communication. The post holder may also be required to contribute to other linked projects.
The post-holder will be based in Kilifi working within an experienced team and research group.
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