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  • Posted: Sep 13, 2018
    Deadline: Not specified
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    The KEMRI Wellcome Trust Research Programme (KWTRP) is based within the KEMRI Centre for Geographic Medical Research - (Coast). Our core activities are funded by the Wellcome Trust. We conduct integrated epidemiological, social, laboratory and clinical research in parallel, with results feeding into local and international health policy. Our research platfor...
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    Assistant Research Officer - (9 Months Contract)

    Reference Number:  ARO070918
    Category: Clinical Healthcare and Research
    Job Grade: 6.01
     
     
    JOB PURPOSE: 

    To undertake sequencing and bioinformatics analysis for a project aimed at understanding the transmission pathways of respiratory viruses in Kenya.  Viruses under investigation include rhinovirus, respiratory syncytial virus, influenza, coronavirus, and human metapneumovirus.

    Description: 

    REPORTS TO:

    • Bioinformatics lead.

    DIRECT REPORTS:

    • None

    INDIRECT REPORTS:  

    • None

    BUDGET RESPONSIBILITY:  

    • None

    KEY RESPONSIBILITIES:

    • Implementing, optimizing and troubleshooting viral pathogen sequencing protocols
    • Developing a multi-species whole genome sequencing method for rhinovirus to investigate sequences in large archive of respiratory samples
    • Molecular diagnostic screening for a range of virus targets in archived and ongoing respiratory samples collections
    • Assembling viral sequence contigs from the raw sequencing reads derived from next generation sequencers
    • Performing phylogenetic analyses, producing reports and presenting arising results
    • Contributing to scientific manuscripts and other dissemination activities

    QUALIFICATIONS:

    • BSc in Medical Laboratory Science and Technology, Molecular Biology Bioinformatics, or similar (Upper second honors or higher)
    • At least 1 year experience in virus molecular diagnostics
    • Experience in virus whole genome sequencing using Sanger and NGS methods
    • Previous experience in rhinovirus typing and sequencing
    • Capability in bioinformatics and phylogenetic analysis of sequence data

    DESIRABLE

    • Undertaken a Post-Graduate Diploma in relevant subject area
    • Knowledge and capability in programming for sequence data manipulations (e.g. R, python)
    • A one-year research experience and evidence of scientific publication/contribution

    SKILLS AND COMPETENCE:

    • Understanding of virus sequencing including NGS and phylogenetics
    • The ability to plan own workload and keep accurate scientific records.
    • Excellent communication and interpersonal skills
    • Ability to organize work to changing priorities is essential

    RELATIONSHIPS:

    • Working in collaboration with members of the Viral Epidemiology and Control (VEC) group (laboratory and research), and with relevant Programme scientists such as those linked to Kilifi Bioinformatics Core (KBiC).

    Method of Application

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