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  • Posted: Mar 27, 2024
    Deadline: Apr 9, 2024
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    The KEMRI Wellcome Trust Research Programme (KWTRP) is based within the KEMRI Centre for Geographic Medical Research - (Coast). Our core activities are funded by the Wellcome Trust. We conduct integrated epidemiological, social, laboratory and clinical research in parallel, with results feeding into local and international health policy. Our research platfor...
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    Research Officer (Sequencing)

    JOB PURPOSE: 

    • Operate and oversee the programme’s Next Gen Sequencing Facility.
    • Manage and maintain the malaria qPCR service
    • Coordinate a Sanger sequencing service with 3rd party providers.
    • Manage and maintain the molecular biology laboratory section

    Description: 

    REPORTING LINES:

    REPORTS TO:

    Head of Biosciences

    INDIRECT REPORT

    Assistant Research Officers, Interns, students.

    FINANCIAL RESPONSIBILITIES:

    Manage all stocks of consumables and reagents for 1,2 & 3 above and maintenance of equipment for 4 above. Provide timely budget reports and invoicing for services provided.

    JOB DIMENSION

    KEY RESPONSIBILITIES:

    • Coordination, operation and maintenance of the Next Generation Sequencing facility and Malaria qPCR service.
    • Maintain a robust stock control and grant billing system to ensure stock-outs are minimized and budgets remain balanced.
    • Ensure all equipment are fully maintained and operational.
    • Work closely with senior scientists to develop sequencing assays.
    • Develop and maintain SOPs and other controlled documentation.
    • Maintain clear and accurate records and results.
    • Coordinate a Sanger sequencing service with 3rd party providers, including sample shipment and payments.
    • Provide a clean and safe working environment for laboratory staff.
    • Monitor and maintain relevant GCLP procedures and standards to deliver a quality service at all times.

    Job Specifications

    • A laboratory-based MSc in a relevant subject, e.g. Biomedical Sciences, Biochemistry, Molecular biology, evolution, genetics.
    • At least 3 years of research experience in a Medical Research Laboratory.

    Desirable

    • Knowledge of GCLPs, QMS and other relevant best practices and standards.
    • Knowledge and experience of implementing, operating and maintaining Quality Assurance & Quality Control systems including Internal Quality Control and External Quality Assurance (EQA) Schemes
    • Computer literacy with proficiency in Microsoft applications and Bioinformatics software.
    • Significant hands-on experience in Next Generation Sequencing, particularly utilising the Illumina MiSeq platform.
    • Significant experience in performing quantitative PCR assays.
    • Strong budgeting and stock management skills.
    • Experience in troubleshooting molecular assays and equipment and working with Service Providers, when required, to provide rapid solutions that ensure minimum downtime.

    COMPETENCIES:

    • Demonstrate high levels of integrity and confidentiality
    • Excellent interpersonal, written, presentation and communication skills
    • Basic analytical, problem solving and critical thinking skills;
    • Team working and ability to work in diverse teams
    • Flexibility, adaptability, multi-tasking and attention to detail.

    PHYSICAL ENVIRONMENT/CONDITIONS

    • Office Work with limited travel to sites.

    Method of Application

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